产品货号:
Z25627
中文名称:
RHEB抗体
英文名称:
Anti-RHEB Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RHEB Antibody |
指标别名 | GTP binding protein Rheb;Ras homolog enriched in brain;RHEB;RHEB2 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB |
基因名称 | RHEB |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Rabbit Rheb polyclonal antibody was raised against a 14 amino acid synthetic peptide from the amino terminus of human Rheb.The immunogen is located within the first 50 amino acids of Rheb. |
计算分子量 | 20kDa |
成分 | Rheb Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | Rheb Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure.While it is expressed at relatively high levels in the brain,Rheb is widely expressed in other tissues and may be induced by growth factor stimulation.Similar to other family members,Rheb triggers activation of the Raf-MEK-MAPK pathway.Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway.TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids,balancing the availability of nutrients with protein translation and cell growth.A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2. |
Uniprot ID | Q15382 |
基因名全称 | Ras homolog enriched in brain |
蛋白名全称 | Ras homolog enriched in brain |
推荐稀释比 | Rheb antibody can be used for the detection of Rheb by Western blot at 2 and 4μg/mL.Antibody validated:Western Blot in rat samples.All other applications and species not yet tested. |
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